WHAT WOULD YOU LIKE TO DO?
Become a student at the #1 Dental School in the United States.
Open to the public, the School of Dentistry clinics provide care for all your dental needs.
Support the world's leading academic and research dental institution.
Come visit the beautiful campus.
Conduct your research at a top five NIH-funded research institution!
Rogerio Castilho, DDS, MS, PhD
Our laboratory focus on the understanding of the “histone code” in the context of tissue injury, chronic inflammatory diseases, and cancer biology. We explore the role of histone acetylation and chromatin remodeling in the control of epithelial functions, including healing, maintenance of epithelial homeostasis and stem cell function. We also explore the epigenetic-driven mechanisms involved in tumor resistance to chemotherapy and ionizing radiation and focus on the use of “epi-drugs” to counteract cancer-driven histone modifications.
The major renovation and expansion at the University of Michigan School of Dentistry, with construction beginning in fall 2018, updates and expands the school’s state-of-the-art facilities for teaching dental students, serving patients from around Michigan and conducting world-class research that advances the dental profession.