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Periodontics and Oral Medicine

Hector Rios, DDS, PhD

 photo Assistant Professor

Division of Periodontology
Department of Periodontics and Oral Medicine
University of Michigan School of Dentistry
1101 N. University Ave
Ann Arbor, MI 48109-1078
Recent Publications


2000 DDS, Universidad del Valle, Cali, Colombia, Dentistry
2001 GPR, Hospital Dentistry, University of Missouri, Kansas City, Truman Medical Center
2006 PhD, Oral Biology/Molecular Biology and Biochemistry, University of Missouri, Kansas City
2009 Certificate, Periodontics, University of Michigan, Ann Arbor

Positions and Employment

2000-2003 Dental Resident, University of Missouri Kansas City/Truman Medical Center
2003-2006 Graduate Student, Oral / Molecular Biology, University of Missouri-Kansas City
2006-2009 Posdoctoral felllow, Department of Periodontics and Oral Medicine, University of Michigan
2009-present Assistant Professor, Department of Periodontics and Oral Medicine, University of Michigan

Professional Affiliations

2002 International Association for Dental Research
2004 American Society of Bone and Mineral Research
2006 American Dental Education Association
2006 American Academy of Periodontology
2010 Diplomate, American Academy of Periodontology


2001 The Biotene Award for Excellence in Hospital Dentistry
2002 NIH Award Training Support
2004 NIDCR Travel Grant Award
2004 ASBMR Presidents Book Award
2004 Plenary Oral presentation at the 2004 ASBMR
2005 Alice Jee Young Investigator Award -International Sun Valley Workshop on Skeletal Tissue Biology
2007 First place award during the 9th Int. Symp. on Perio. and Rest. Dentistry
2008 American Academy of Peridontology Educator’s Award
2009 4th Osteology Foundation Expert Meeting- Invited participant

Recent Publications

Rosselli-Murai LK, Almeida LO, Zagni C, Galindo-Moreno P, Padial-Molina M, Volk SL, Murai MJ, Rios HF, Squarize CH, Castilho RM. Periostin Responds to Mechanical Stress and Tension by Activating the MTOR Signaling Pathway. PLoS One. 2013 Dec 13;8(12):e83580.

Park CH, Rios HF, Taut AD, Padial-Molina M, Flanagan CL, Pilipchuk SP, Hollister SJ, Giannobile WV. Image-Based, Fiber Guiding Scaffolds: A Platform for Regenerating Tissue Interfaces. Tissue Eng Part C Methods. 2013 Dec 14. [Epub ahead of print] PubMed PMID: 24188695.

Padial-Molina M, Volk SL, Rodriguez JC, Marchesan JT, Galindo-Moreno P, Rios HF. Tumor necrosis factor-α and Porphyromonas gingivalis lipopolysaccharides decrease periostin in human periodontal ligament fibroblasts. J Periodontol. 2013 May;84(5):694-703.

Padial-Molina M, Marchesan JT, Taut AD, Jin Q, Giannobile WV, Rios HF. Methods to validate tooth-supporting regenerative therapies. Methods Mol Biol. 2012;887:135-48.

Benavides E, Rios HF, Ganz SD, An CH, Resnik R, Reardon GT, Feldman SJ, Mah JK, Hatcher D, Kim MJ, Sohn DS, Palti A, Perel ML, Judy KW, Misch CE, Wang HL. Use of cone beam computed tomography in implant dentistry: the International Congress of Oral Implantologists consensus report. Implant Dent. 2012 Apr;21(2):78-86.

Galindo-Moreno P, Padial-Molina M, Avila G, Rios HF, Hernández-Cortés P, Wang HL. Complications associated with implant migration into the maxillary sinus cavity. Clin Oral Implants Res. 2012 ct;23(10):1152-60.

Park CH, Rios HF, Jin Q, Sugai JV, Padial-Molina M, Taut AD, Flanagan CL, Hollister SJ, Giannobile WV. Tissue engineering bone-ligament complexes using fiber-guiding scaffolds. Biomaterials. 2012 Jan;33(1):137-45.

Rios HF, Lin Z, Oh B, Park CH, Giannobile WV. Cell- and gene-based therapeutic strategies for periodontal regenerative medicine. J Periodontol. 2011 Sep;82(9):1223-37.

Ma D, Zhang R, Sun Y, Rios HF, Haruyama N, Han X, Kulkarni AB, Qin C, Feng JQ. A novel role of periostin in postnatal tooth formation and mineralization. J Biol Chem. 2011 Feb 11;286(6):4302-9.

Park CH, Rios HF, Jin Q, Bland ME, Flanagan CL, Hollister SJ, Giannobile WV. Biomimetic hybrid scaffolds for engineering human tooth-ligament interfaces. Biomaterials. 2010 Aug;31(23):5945-52.

Lin Z, Rios HF, Volk SL, Sugai JV, Jin Q, Giannobile WV. Gene Expression Dynamics During Bone Healing and Osseointegration. J Periodontol. 2010 Dec 13. [Epub ahead of print] PubMed PMID: 21142982.

Lu X, Rios HF, Jiang B, Xing L, Kadlcek R, Greenfield EM, Luo G, Feng JQ. A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots. Eur J Oral Sci. 2009 Dec;117(6):625-35. PMID: 20121924.

Rios HF, Avila G, Galindo P, Wang HL. The Influence of Remaining Alveolar Bone Upon Lateral Window Sinus Augmentation Implant Survival. Implant Dentistry, 2009 Oct.

Rios HF, Ma D, Bonewald LF, Giannobile WV, Conway S, Feng JQ. Periostin is essential for the integrity and function of the periodontal ligament during occlusal loading. J Periodontol. August 2008.

Avila G, Galindo P, Rios H, Wang HL. Immediate implant loading: current status from available literature. Implant Dent. 2007 Sep;16(3):235-45. Review. PubMed PMID: 17846539.

Feng JQ, Ward LM, Liu S, Lu Y, Xie Y, Yuan B, Yu X, Rauch F, Davis SI, Zhang S, Rios H, Drezner MK, Quarles LD, Bonewald LF, White KE. Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism. Nat Genet. 2006 Nov;38(11):1310-5. Epub 2006 Oct 8. PubMed PMID: 17033621; PubMed Central PMCID: PMC1839871.

Rios H, Koushik SV, Wang H, Wang J, Zhou HM, Lindsley A, Rogers R, Chen Z, Maeda M, Kruzynska-Frejtag A, Feng JQ, Conway SJ. periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype. Mol Cell Biol. 2005 Dec;25(24):11131-44. PubMed PMID: 16314533; PubMed Central PMCID: PMC1316984.

Ling Y, Rios HF, Myers ER, Lu Y, Feng JQ, Boskey AL. DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis. J Bone Miner Res. 2005 Dec;20(12):2169-77. Epub 2005 Aug 22. PubMed PMID: 16294270; PubMed Central PMCID: PMC1456072.

Rios HF, Ye L, Dusevich V, Eick D, Bonewald LF, Feng JQ. DMP1 is essential for osteocyte formation and function. J Musculoskelet Neuronal Interact 2005 Oct-Dec;5(4):325-7. PMID: 16340123.