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Biologic and Materials Sciences & Prosthodontics

Geng Lab

Jian-Guo Geng, MD, PhD

Biologic & Materials Sciences
Associate Professor

Geng Research

Research Activity

My research has been focused on cell adhesion and migration of leukocytes, platelets, endothelial cells and tumor cells for their functional roles in inflammation, thrombosis and cancer growth and metastasis in the past. We are now interested in how cell signaling pathways modulate adult stem cells, especially for fast-cycling intestinal stem cells (ISCs) in gut repair following chemoradiotherapy. In addition, we are studying how to induce pluripotent stem cells and their progenitors in vivo by small molecules for organ regeneration.

GFP/Robo1 for GFPhigh ISCs (Nature 501:107, 2013)