Mentors (U-M TOPICs)

University of Michigan’s TMJD and
Orofacial Pain Interdisciplinary Consortium
Training Grant (K12DE023574)

Faculty Title Department Research Interest
Brian D. Athey, Ph.D. Professor and Chair Computational Medicine and Bioinformatics Integrative Biomedical Informatics and Translational Bioinformatics leading to increased understanding of systems models and mechanisms of human health and disease particularly as it contributes to individualized medicine.
Michael Lee Boehnke, Ph.D. Professor Biostatistics Statistical methods for genetic analysis of common human diseases and traits with application to type 2 diabetes, diabetes related traits and bipolar disorder.
Thomas M. Braun, Ph.D. Associate Professor Biostatistics Correlated/longitudinal data; Phase I clinical trial design.
Daniel J. Clauw, M.D. Professor Anesthesiology Internal Medicine-Rheumatology 1) Fibromyalgia and central pain syndromes 2) Stress 3) Mechanisms of pain processing 4) somatic syndromes
David J. Fink, M.D. Professor and Chair Neurology Pathogenesis of pain, and the development of novel gene transfer-based therapeutics for pain.
David A. Fox, M.D. Professor Internal Medicine-Rheumatology The interaction of the immune system with target tissues, in order to understand processes that cause tissue remodeling and destruction in autoimmune disease.
Renny T Francheschi, Ph.D. Professor Periodontics and Oral Medicine Biological Chemistry Transcriptional control of osteoblast differentiation with emphasis on the role of Runx2 transcription factor and the control of Runx2 activity by the ERK/MAPK pathway.
William V. Giannobile, D.D.S., D. Med. Sc. Professor Periodontics and Oral Medicine Biomedical Engineering Tissue Engineering, periodontal diseases, clinical trials, bone regeneration, disease diagnostics.
Carmen R. Green, M.D. Professor, Faculty Associate Anesthesiology RCGD-Research Center for Group Dyn 1) Health care utilization and access to pain care; 2) Health care provider variability in pain management decision-making; 3) Racial, ethnic, age, gender, and class influence on pain management outcomes; 4) Health status and health care disparities (age, race, gender, and class) 5) Safety, quality, outcomes and pain management education in acute, chronic, and cancer pain management; 6) Health and health care policy including elder, minority, and women’s health and health care.
Richard E. Harris, Ph.D. Assistant Professor Anesthesiology Internal Medicine – Rheumatology Pain, Neuroimaging, Clinical
Vesa M. Kaartinen, Ph.D., M.S. Associate Professor Biologic and Material Sciences Growth factor signaling in craniofacial and cardiac development.
Sunil D. Kapila, B.D.S., Ph.D., M.S. Professor and Chair Orthodontics and Pediatric Dentistry  Molecular, cellular and in vivo mechanisms of hormonal modulation of cartilage degradation; bioengineering of heterogenous fibrocartilaginous tissues using mechano-biologic stimulation of mesenchymal stem cells; periodontal osteolysis mediated by matrix metalloproteinases.
David H. Kohn, Ph.D., M.S. Professor Biologic and Material Sciences Biomedical Engineering Biomimetics, biomechanics, biomaterials and interfacial phenomena related to mineralized tissues and mineralized tissue replacement/regeneration.
Paul K. Krebsbach, D.D.S., Ph.D. Professor and Chair Biologic and Material Sciences Biomedical Engineering Cell and molecular biology of mineralized tissues with an emphasis on bone tissue engineering in gene therapy-directed osteogenesis; bone marrow stromal cell biology related to bone growth and differentiation.
Steve L. Kunkel, Ph.D., M.S. Professor, Associate Dean Pathology Graduate School Administration Cellular and molecular mechanisms of cytokine networks operative in immune/inflammatory reactions and host defenses.
Lisa M. Larkin, Ph.D., M.S. Associate Professor Molecular and Integrative Physiology Biomedical Engineering Skeletal Tissue Engineering and Muscle Mechanics Research
Peter X. Ma, Ph.D., M.S. Professor Biologic and Material Sciences Biomedical Engineering Chemical and architectural structures of biomaterials and polymer scaffolds affect cell behavior and function; developing release systems for controlled delivery of factors in tissue-engineering scaffolds; during regeneration of various tissues in vitro and in vivo.
Laurie Kay McCauley, Ph.D., D.D.S., M.S. Professor and Chair Periodontics and Oral Medicine Pathology Endocrine mediators of bone remodeling with a focus on parathyroid hormones and their anabolic actions; skeletal metastasis and the impact of the bone marrow microenvironment on tumor establishment; the impact and therapeutic potential of parathyroid hormone in craniofacial osseous wound healing.
Yuji Mishina, Ph.D. Associate Professor Biologic and Material Sciences   Craniofacial development, mouse genetics, growth factor signaling, embryogenesis
Michael D. Morris, Ph.D. Professor Chemistry Development, pathology and biomechanics of musculoskeletal tissue, Raman and fluorescence spectroscopy and imaging of musculoskeletal tissue, solid state NMR of musculoskeletal tissue.
Gilbert S. Omenn, M.D., Ph.D. Professor Computational Medicine and Bioinformatics Human Genetics Cancer proteomics and chemoprevention; mechanisms of genetic predispositions to risks from environmental and occupational exposures especially for cancers and cardiovascular disease; pharmacogenetics and pharmacogenomics.
Pierchala, Brian, Ph.D. Assistant Professor Biologic and Material Sciences Mechanisms of neural circuit development, maintenance and degeneration.
Barbara D. Reed, M.D. Professor Family Medicine Pain, Clinical
Deneen Marie Wellik, Ph.D. Associate Professor Internal Medicine Molecular Medicine and Genetics Cell and Developmental Biology Function of Hox genes during mammalian organogenesis. During limb development, integration of the musculoskeletal system, axial patterning, kidney development and prostate development. Characterizing the roles of these genes during gut morphogenesis and pancreatic development.
Edward M. Wojtys, M.D., B.S. Professor Orthopaedic Surgery MedSport Knee injuries in sports, the female athlete, ACL injury, mechanisms and injury prevention, ACL replacements, sports medicine, epidemiology and osteoarthritis of the knee.
James H.  Woods, Ph.D. Professor Pharmacology Psychology Behavioral pharmacology; drug tolerance; dependence; and reinforcement.
Jon K. Zubieta, M.D., Ph.D. Research Professor, Professor Molecular and Behavioral Neuroscience Institute Psychiatry Radiology Neurochemical and functional neuroimaging in humans.  Research themes include neurobiological mechanisms involved in stress responses, mood regulation and substance abuse.