Loesche WJ. Schork A. Terpenning MS. Chen YM. Kerr C. Dominguez BL. The relationship between dental disease and cerebral vascular accident in elderly United States veterans. Annals of Periodontology. 3(1):161-74, 1998 Jul. [ABSTRACT]

Loesche WJ. Taylor G. Giordano J. Hutchinson R. Rau CF. Chen YM. Schork MA. A logistic regression model for the decision to perform access surgery. Journal of Clinical Periodontology. 24(3):171-9, 1997 Mar. [ABSTRACT]

Loesche WJ. Kazor CE. Taylor GW. The optimization of the BANA test as a screening instrument for gingivitis among subjects seeking dental treatment. Journal of Clinical Periodontology. 24(10):718-26, 1997 Oct. [ABSTRACT]

Loesche WJ. Giordano JR. Treatment paradigms in periodontal disease. [Review] [32 refs] Compendium of Continuing Education in Dentistry (Jamesburg, NJ). 18(3):221-6, 228-30, 232 passim; quiz 234, 1997 Mar. [ABSTRACT]

Makinen KK. Makinen PL. Loesche WJ. Syed SA. Purification and general properties of an oligopeptidase from Treponema denticola ATCC 35405--a human oral spirochete. Archives of Biochemistry & Biophysics. 316(2):689-98, 1995 Feb 1. [ABSTRACT]

Watson MR. Bretz WA. Loesche WJ. Presence of Treponema denticola and Porphyromonas gingivalis in children correlated with periodontal disease of their parents. Journal of Dental Research. 73(10):1636-40, 1994 Oct. [ABSTRACT]

Loesche WJ. Periodontal disease as a risk factor for heart disease. [Review] [34 refs] Compendium. 15(8):976, 978-82, 985-6 passim; quiz 992, 1994 Aug. [ABSTRACT]

Loesche WJ. Giordano JR. Metronidazole in periodontitis V: debridement should precede medication. Compendium. 15(10):1198, 1201, 1203 passim; quiz 1218, 1994 Oct. [ABSTRACT]

Loesche WJ. Grossman N. Giordano J. Metronidazole in periodontitis (IV). The effect of patient compliance on treatment parameters. Journal of Clinical Periodontology. 20(2):96-104, 1993 Feb. [ABSTRACT]

Loesche WJ. Bacterial mediators in periodontal disease. [Review] [88 refs] Clinical Infectious Diseases. 16 Suppl 4:S203-10, 1993 Jun. [ABSTRACT]

Bretz WA. Eklund SA. Radicchi R. Schork MA. Schork N. Schottenfeld D. Lopatin DE. Loesche WJ. The use of a rapid enzymatic assay in the field for the detection of infections associated with adult periodontitis. Journal of Public Health Dentistry. 53(4):235-40, 1993 Fall. [ABSTRACT]

Loesche WJ. Lopatin DE. Stoll J. van Poperin N. Hujoel PP. Comparison of various detection methods for periodontopathic bacteria: can culture be considered the primary reference standard?. Journal of Clinical Microbiology. 30(2):418-26, 1992 Feb. [ABSTRACT]

Loesche WJ. Lopatin DE. Giordano J. Alcoforado G. Hujoel P. Comparison of the benzoyl-DL-arginine-naphthylamide (BANA) test, DNA probes, and immunological reagents for ability to detect anaerobic periodontal infections due to Porphyromonas gingivalis, Treponema denticola, and Bacteroides forsythus. Journal of Clinical Microbiology. 30(2):427-33, 1992 Feb. [ABSTRACT]

Loesche WJ. Giordano JR. Hujoel P. Schwarcz J. Smith BA. Metronidazole in periodontitis: reduced need for surgery. Journal of Clinical Periodontology. 19(2):103-12, 1992 Feb. [ABSTRACT]

Loesche WJ. DNA probe and enzyme analysis in periodontal diagnostics. Journal of Periodontology. 63(12 Suppl):1102-9, 1992 Dec. [ABSTRACT]

Loesche WJ. The specific plaque hypothesis and the antimicrobial treatment of periodontal disease. Dental Update. 19(2):68, 70-2, 74, 1992 Mar. [ABSTRACT]

Loesche WJ. Schmidt E. Smith BA. Morrison EC. Caffesse R. Hujoel PP. Effects of metronidazole on periodontal treatment needs. Journal of Periodontology. 62(4):247-57, 1991 Apr. [ABSTRACT]

Watson MR. Lopatin DE. Bretz WA. Ertel IJ. Loesche WJ. Detection of two anaerobic periodontopathogens in children by means of the BANA and ELISA assays. Journal of Dental Research. 70(7):1052-6, 1991 Jul. [ABSTRACT]

Loesche WJ. Current research in diagnostic methods for assessing periodontal disease and its future impact. [Review] [27 refs] Journal / Canadian Dental Association. Journal de l Association Dentaire Canadienne. 57(7):574-8, 1991 Jul. [ABSTRACT]

Loesche WJ. Role of anaerobic bacteria in periodontal disease. Annals of Otology, Rhinology, & Laryngology - Supplement. 154:43-5, 1991 Sep. [ABSTRACT]

Loesche WJ. Bretz WA. Lopatin D. Stoll J. Rau CF. Hillenburg KL. Killoy WJ. Drisko CL. Williams R. Weber HP. et al. Multi-center clinical evaluation of a chairside method for detecting certain periodontopathic bacteria in periodontal disease. Journal of Periodontology. 61(3):189-96, 1990 Mar. [ABSTRACT]

Hujoel PP. Loesche WJ. DeRouen TA. Assessment of relationships between site-specific variables. Journal of Periodontology. 61(6):368-72, 1990 Jun. [ABSTRACT]

Loesche WJ. Bretz WA. Kerschensteiner D. Stoll J. Socransky SS. Hujoel P. Lopatin DE. Development of a diagnostic test for anaerobic periodontal infections based on plaque hydrolysis of benzoyl-DL-arginine-naphthylamide. Journal of Clinical Microbiology. 28(7):1551-9, 1990 Jul. [ABSTRACT]

Hujoel PP. Moulton LH. Loesche WJ. Estimation of sensitivity and specificity of site-specific diagnostic tests [published erratum appears in J Periodontal Res 1990 Nov;25(6):377]. Journal of Periodontal Research. 25(4):193-6, 1990 Jul. [ABSTRACT]

Loesche WJ. Giordano J. Hujoel PP. The utility of the BANA test for monitoring anaerobic infections due to spirochetes (Treponema denticola) in periodontal disease. Journal of Dental Research. 69(10):1696-702, 1990 Oct. [ABSTRACT]

Loesche WJ. Rationale for the use of antimicrobial agents in periodontal disease. [Review] [71 refs] International Journal of Technology Assessment in Health Care. 6(3):403-17, 1990. [ABSTRACT]

Hujoel PP. Loesche WJ. Efficiency of split-mouth designs. Journal of Clinical Periodontology. 17(10):722-8, 1990 Nov. [ABSTRACT]

Makinen KK. Chen CY. Makinen PL. Ohta K. Loesche WJ. The benzoylarginine peptidase from Treponema denticola (strain ASLM), a human oral spirochaete: evidence for active-site carboxyl groups. Molecular Microbiology. 4(8):1413-7, 1990 Aug. [ABSTRACT]

Bretz WA. Lopatin DE. Loesche WJ. Benzoyl-arginine naphthylamide (BANA) hydrolysis by Treponema denticola and/or Bacteroides gingivalis in periodontal plaques. Oral Microbiology & Immunology. 5(5):275-9, 1990 Oct. [ABSTRACT]

Suzuki M. Loesche WJ. Ceruloplasmin can substitute for rabbit serum in stimulating the growth of Treponema denticola. Infection & Immunity. 57(2):643-4, 1989 Feb. [ABSTRACT]

Morinushi T. Lopatin DE. Syed SA. Bacon G. Kowalski CJ. Loesche WJ. Humoral immune response to selected subgingival plaque microorganisms in insulin-dependent diabetic children. Journal of Periodontology. 60(4):199-204, 1989 Apr. [ABSTRACT]

Baum BJ. Burstone CJ. Dubner R. Goldhaber P. Levine MJ. Loesche WJ. Terranova V. Advances in diagnosis and detection of oral diseases. Advances in Dental Research. 3(1):7-13, 1989 May. [ABSTRACT]

Loesche WJ. [Antibiotic therapy as part of periodontal therapy]. [German] Phillip Journal. 6(2):95-104, 1989 Apr.

Loesche WJ. Robinson JP. Flynn M. Hudson JL. Duque RE. Reduced oxidative function in gingival crevicular neutrophils in periodontal disease. Infection & Immunity. 56(1):156-60, 1988 Jan. [ABSTRACT]

Adriaens PA. De Boever JA. Loesche WJ. Bacterial invasion in root cementum and radicular dentin of periodontally diseased teeth in humans. A reservoir of periodontopathic bacteria. Journal of Periodontology. 59(4):222-30, 1988 Apr. [ABSTRACT]

Adriaens PA. Edwards CA. De Boever JA. Loesche WJ. Ultrastructural observations on bacterial invasion in cementum and radicular dentin of periodontally diseased human teeth. Journal of Periodontology. 59(8):493-503, 1988 Aug. [ABSTRACT]

Syed SA. Salvador SL. Loesche WJ. Enzyme profiles of oral spirochetes in RapID-ANA system. Journal of Clinical Microbiology. 26(10):2226-8, 1988 Oct. [ABSTRACT]

Schmidt EF. Webber RL. Ruttimann UE. Loesche WJ. Effect of periodontal therapy on alveolar bone as measured by subtraction radiography. Journal of Periodontology. 59(10):633-8, 1988 Oct. [ABSTRACT]

Schmidt EF. Bretz WA. Hutchinson RA. Loesche WJ. Correlation of the hydrolysis of benzoyl-arginine naphthylamide (BANA) by plaque with clinical parameters and subgingival levels of spirochetes in periodontal patients. Journal of Dental Research. 67(12):1505-9, 1988 Dec. [ABSTRACT]

Loesche WJ. The role of spirochetes in periodontal disease. Advances in Dental Research. 2(2):275-83, 1988 Nov.

Loesche WJ. Syed SA. Stoll J. Trypsin-like activity in subgingival plaque. A diagnostic marker for spirochetes and periodontal disease?. Journal of Periodontology. 58(4):266-73, 1987 Apr. [ABSTRACT]

Loesche WJ. Schmidt E. Smith BA. Caffessee R. Stoll J. Metronidazole therapy for periodontitis. Journal of Periodontal Research. 22(3):224-6, 1987 May.

Salvador SL. Syed SA. Loesche WJ. Comparison of three dispersion procedures for quantitative recovery of cultivable species of subgingival spirochetes. Journal of Clinical Microbiology. 25(11):2230-2, 1987 Nov. [ABSTRACT]

Ohta K. Makinen KK. Loesche WJ. Purification and characterization of an enzyme produced by Treponema denticola capable of hydrolyzing synthetic trypsin substrates. Infection & Immunity. 53(1):213-20, 1986 Jul. [ABSTRACT]

Loesche WJ. The identification of bacteria associated with periodontal disease and dental caries by enzymatic methods. Oral Microbiology & Immunology. 1(1):65-72, 1986 Nov.

Loesche WJ. The therapeutic use of antimicrobial agents in patients with periodontal disease. Scandinavian Journal of Infectious Diseases - Supplementum. 46:106-14, 1985. [ABSTRACT]

Loesche WJ. Syed SA. Schmidt E. Morrison EC. Bacterial profiles of subgingival plaques in periodontitis. Journal of Periodontology. 56(8):447-56, 1985 Aug. [ABSTRACT]

Loesche WJ. Syed SA. Morrison EC. Kerry GA. Higgins T. Stoll J. Metronidazole in periodontitis. I. Clinical and bacteriological results after 15 to 30 weeks. Journal of Periodontology. 55(6):325-35, 1984 Jun. [ABSTRACT]

Loesche WJ. Possibilities for treating periodontal disease as specific anaerobic infections. Journal / Canadian Dental Association. Journal de l Association Dentaire Canadienne. 50(6):467-72, 1984 Jun.

Gusberti FA. Syed SA. Bacon G. Grossman N. Loesche WJ. Puberty gingivitis in insulin-dependent diabetic children. I. Cross-sectional observations. Journal of Periodontology. 54(12):714-20, 1983 Dec. [ABSTRACT]

Loesche WJ. Gusberti F. Mettraux G. Higgins T. Syed S. Relationship between oxygen tension and subgingival bacterial flora in untreated human periodontal pockets. Infection & Immunity. 42(2):659-67, 1983 Nov. [ABSTRACT]

Kornman KS. Loesche WJ. Effects of estradiol and progesterone on Bacteroides melaninogenicus and Bacteroides gingivalis. Infection & Immunity. 35(1):256-63, 1982 Jan. [ABSTRACT]

Vandenbergh PA. Syed SA. Gonzalez CF. Loesche WJ. Olsen RH. Plasmid content of some oral microorganisms isolated from subgingival plaque. Journal of Dental Research. 61(3):497-501, 1982 Mar. [ABSTRACT]

Laughon BE. Syed SA. Loesche WJ. Rapid identification of Bacteroides gingivalis. Journal of Clinical Microbiology. 15(2):345-6, 1982 Feb.

Loesche WJ. Syed SA. Laughon BE. Stoll J. The bacteriology of acute necrotizing ulcerative gingivitis. Journal of Periodontology. 53(4):223-30, 1982 Apr. [ABSTRACT]

Laughon BE. Syed SA. Loesche WJ. API ZYM system for identification of Bacteroides spp., Capnocytophaga spp., and spirochetes of oral origin. Journal of Clinical Microbiology. 15(1):97-102, 1982 Jan. [ABSTRACT]

Loesche WJ. Syed SA. Morrison EC. Laughon B. Grossman NS. Treatment of periodontal infections due to anaerobic bacteria with short-term treatment with metronidazole. Journal of Clinical Periodontology. 8(1):29-44, 1981 Feb. [ABSTRACT]

Loesche WJ. Plaque control in the handicapped: the treatment of specific plaque infections. Journal / Canadian Dental Association. Journal de l Association Dentaire Canadienne. 47(10):649-56, 1981 Oct.

Kornman KS. Loesche WJ. The subgingival microbial flora during pregnancy. Journal of Periodontal Research. 15(2):111-22, 1980 Mar.

Lopatin DE. Kornman KS. Loesche WJ. Modulation of immunoreactivity to periodontal disease-associated microorganisms during pregnancy. Infection & Immunity. 28(3):713-8, 1980 Jun. [ABSTRACT]

Loesche WJ. Clinical and microbiological aspects of chemotherapeutic agents used according to the specific plaque hypothesis. Journal of Dental Research. 58(12):2404-12, 1979 Dec. [ABSTRACT]

Syed SA. Loesche WJ. Bacteriology of human experimental gingivitis: effect of plaque age. Infection & Immunity. 21(3):821-9, 1978 Sep.

Loesche WJ. Syed SA. Bacteriology of human experimental gingivitis: effect of plaque and gingivitis score. Infection & Immunity. 21(3):830-9, 1978 Sep.

Loesche WJ. Periodontal disease and the treponemes. pp. 261-75. [Review] [59 refs] In: Johnson RC, ed. The biology of parasitic spirochetes. New York, Academic Press, 1976. QW 155 S989 1975b.

Loesche WJ. Paunio KU. Woolfolk MP. Hockett RN. Collagenolytic activity of dental plaque associated with periodontal pathology. Infection & Immunity. 9(2):329-36, 1974 Feb.

Kraal JH. Loesche WJ. Rabbit polymorphonuclear leukocyte migration in vitro in response to dental plaque. Journal of Periodontal Research. 9(1):1-9, 1974.

Loesche WJ. Nafe D. Reduction of supragingival plaque accumulations in institutionalized Down's syndrome patients by periodic treatment with topical kanamycin. Archives of Oral Biology. 18(9):1131-43, 1973 Sep.

Loesche W. Green E. Comparison of various plaque parameters in individuals with poor oral hygiene. Journal of Periodontal Research. 7(2):173-9, 1972.

Loesche WJ. Syed S. Hockett RN. Nafe D. Effect of topical kanamycin on plaque, plaque mass, and gingivitis in institutionalized individuals. Journal of Periodontal Research. (10):34-6, 1972.

Loesche WJ. Hockett R. Syed SA. Evaluation of Kanamycin as an aid in the isolation of Bacteroides melaninogenicus from dental plaque. Archives of Oral Biology. 16(7):813-5, 1971 Jul.

Gordon DF. Stutman M. Loesche WJ. Improved isolation of anaerobic bacteria from the gingival crevice area of man. Applied Microbiology. 21(6):1046-50, 1971 Jun.

Loesche WJ. Oxygen sensitivity of various anaerobic bacteria. Applied Microbiology. 18(5):723-7, 1969 Nov.

Loesche W. The bacteriology of the fuso-spirochetal complex. Journal of Periodontology. 39(1):45, 1968 Jan.

Loesche WJ. Importance of nutrition in gingival crevice microbial ecology. Periodontics. 6(6):245-9, 1968 Dec.

Loesche WJ. Gibbons RJ. A practical scheme for identification of the most numerous oral gram negative anaerobic rods. Archives of Oral Biology. 10(4):723-5, 1965 Jul-Aug.


BIOSKETCHES | EDUCATION | PUBLICATIONS | LINKS | QUESTIONS | EMAIL | HOME