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Contact Info

1011 N University Ave School of Dentistry #5228
University of Michigan
Ann Arbor, MI 48109-1078
Phone: (734) 615-1642

Research Interests

My lab focuses on three main areas of research. One area involves understanding the underlying cell-matrix interactions that govern disease progression in inflammatory diseases such as periodontal tissues. These studies encompass both basic cell and molecular biology studies and patient/translational investigations. Another related area that our lab has recently embarked on relates to expanding our understanding of the mechanisms by which matrix metalloproteinases (MMPs) triggered by inflammatory disease-modulated-matrices may enhance osteoclast activity and diminish osteoblast differentiation. Lastly, the other main area of research in my lab involves understanding the cell-matrix interactions that govern cell survival and invasion/migration of squamous cell carcinomas.

Current Research

• Fibronectin Regulation of Carcinoma Apoptosis, NIH/NIDCR
• Apoptosis Regulated by Fibronectin Signaling Pathways, NIH/NIDCR
• Apoptosis Regulated by Fibronectin Signaling Pathways - Diversity Supplement, NIH/NIDCR
• Fibronectin Fragment-Induced Osteolysis Mediated by MMPs, NIH/NIDCR
• Apoptotic Biomarkers of Periodontal Disease, UM MCOHR/GCRC
• Role of Rap1 in Cadherin and Integrin Mediated Cross-Talk in Oral Keratinocytes, NIH/NIDCR

Lab Personnel

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