Drach Lab - publications

  • Komazin, G. L.B. Townsend, and J.C. Drach. Role of a Mutation in Human Cytomegalovirus Gene UL104 in Resistance to Benzimidazole Ribonucleosides. J. Virol., 78: 710–715, 2004.
  • Porcari, A.R., R.G. Ptak, K.Z. Borysko, J.M. Breitenbach, J.C. Drach and L.B. Townsend. Synthesis and antiviral activity of 2-substituted analogs of triciribine. Nucleosides, Nucleotides & Nucleic Acids, 22: 2171-2193, 2003.
  • Komazin, G., R.G. Ptak, B.T. Emmer, L.B. Townsend and J.C. Drach.. Resistance of Human Cytomegalovirus to the Benzimidazole L-Ribonucleoside 1263W94 Maps to UL27. J. Virol., 77: 11499-11506, 2003.
  • Shin, H-C., C.P. Landowski, D. Sun, B.S.Vig, I. Kim, S. Mittal, M.Lane, G.Rosania, J.C. Drach and G.L. Amidon. Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum. Biochem. Biophys. Res. Commun., 307: 696–703, 2003.
  • Wang, R., X. Chen, J.C. Drach, E.R. Kern and J. Zemlicka. Synthesis and biological activity of 2-aminopurine methylenecyclopropane analogues of nucleosides. Nucleosides & Nucleotides & Nucleic Acids, 22: In press, April 2003.
  • Williams, S.L., C.B. Hartline, N.L. Kushner, E.A. Harden, D.J. Bidanset, J.C. Drach, L.B. Townsend, M.R. Underwood, K.K. Biron and E.R. Kern. In Vitro Activities of Benzimidazole D- and L- Ribonucleosides Against Herpesviruses. Antimicrob. Agents Chemother. 47: 2186-2192, 2003.
  • Chen, X., E.R. Kern, J.C. Drach, E. Gullen, Y-c. Cheng and J. Zemlicka. Structure-Activity Relationships of (S,Z)-2-Aminopurine Methylenecyclopropane Analogues of Nucleosides. Variation of Purine-6 Substituents and Activity against Herpesviruses and Hepatitis B Virus. J. Med. Chem., 46: 1531-1537, 2003.
  • Gudmundsson, K.S., J.D. Williams, J.C. Drach, and L.B. Townsend. Synthesis and Antiviral Activity of Novel Erythrofuranosyl Imidazo[1,2-a]pyridine C-Nucleosides Constructed via Palladium Coupling of Iodoimidazo[1,2-a]pyridines and Dihydrofuran. J. Med. Chem. 46: 1449 – 1455, 2003.
  • Scholz, B., S. Rechter, J.C. Drach, L.B. Townsend and E. Bogner, Identification of the ATP-binding site in the terminase subunit pUL56 of human cytomegalovirus. Nucleic Acids Research 31: 1426 – 1433, 2003.
  • Baldanti, F, A. Sarasini, J.C. Drach, J. Zemlicka, and G. Gerna. Z-isomers of 2-hydroxymethylcyclopropylidenemethyl adenine (synadenol) and guanine (synguanol) are active against ganciclovir- and foscarnet-resistant human cytomegalovirus UL97 mutants. Antiviral Res., 56: 273 – 278, 2002