Volunteers needed for a 6 month research study on gum recession.

Eligible participants will receive soft tissue grafting surgery and dental cleanings at no charge.

Major Inclusion Criteria:

• Gum recession requiring soft tissue grafting
• Between the ages of 18-70
• Must be a non-smoker

For more information please call or e-mail:
Michigan Center for Oral Health Research MCOHR
Lana Huffman
Phone: 734 998-6721
E-mail: lanahuff@umich.edu

Healthy individuals in need of regular dental cleaning or patients with gum disease (periodontitis) needed for a six month research study. Study involves donation of oral fluid samples, dental cleaning or periodontal treatment, and follow-up visits.

Eligible participants will receive a full mouth examination, and dental cleaning or deep cleaning (scaling and root planing) at no cost.

Major Inclusion Criteria:

• Overall good health
• Patients with gum disease OR healthy patients in need of regular dental cleaning
• No antibiotics or NSAIDs use

For more information please call:
Michigan Center for Oral Health Research MCOHR
 Sindhu Halubai
Phone: 734 615-3086
E-mail: oralresearch@umich.edu

Volunteers needed for a research study on periodontitis (gum disease).  Eligible participants will receive conventional treatment for gum disease, including surgery, and possible treatment with medication.  All research related work will be performed at no charge.  In addition to therapy, participants will self-administer a bone building medication or placebo at home over a 6 week period.

Major Inclusion Criteria:

• Gum disease
• Over 30 years of age
• No current bone diseases or
• No uncontrolled diabetes or decreased calcium absorption

IRBMED Number: 2004-0732
Date of Approval: 04/28/2005

Suffering from recurrent cold sores?
You may be eligible for our study!

Our cold sore feasibility study will test laboratory methods to quantify and identify virus types and evaluate our patient education materials and clinical study flow. We are recruiting a group of 65 generally healthy subjects, 18-80 years old, with recurrent cold sores (at least three cold sores per year) to help us prepare future treatment studies of a novel topical treatment of cold sores. Participants will be enrolled with an active cold sore lesion and during the first clinic visit a short history, a photograph of the lesion and a specimen (blister swab with a q-tip) will be obtained. Forty patients participate for this visit only. Twenty subjects will return for daily visits (max. 12 visits) until the lesion is healed and participate in evaluation of our educational materials and the calibration of study personnel. Although currently no active treatment will be provided, this will help to develop our future treatment study.

Participants for one-visit only will receive $15 as incentive. Participants who return daily may receive up to $130.

You will find further information in the PDF document: ColdSore_Flyer.pdf.

If you are interested in being part of this study, please contact the Michigan Center for Oral Health Research (MCOHR) by phone (734) 998-6721 or email us at oralresearch@umich.edu.

IRBMED No.: 2005-0225
Expiry date: My 3, 2007 GCRC #2120

1. PI Giannobile, DDS, DMSc, Title: A 9 Month, 3-Arm, Multicenter Clinical Trial of Treatment with Periocline(TM) Gel (2% Minocycline HCL) for adjunctive use to Scaling and Root Planing in Adults with Periodontal Disease where Periocline(TM) is compared to SRP and SRP with Vehicle: Multicenter Randomized Trial using 3rd Party Outcome Evaluation.
    

2. PI Giannobile, DDS, DMSc, Title: Integrated Microfluidic System for Oral Diagnostics.
    

3. PI McCauley, DDS, PhD, Title: Impact of Parathyroid Hormone (1-34) on Osseous Regeneration in the Oral Cavity.
    

4. PI: Peters, DMD, PhD, Title: Cold Sore Feasibility Study.
    

5. PI Y. Kapila, DDS, PhD, Title: Apoptotic Biomarkers of Periodontal Disease.
    

6. PI Benavides, DDS, PhD, Title: Computed Tomography for Periodontal Disease.
    

7. PI Feinberg, DDS, PhD, Title: Intraoral Grafting of Ex-Vivo Produced Oral Mucosa Composites: Proof of Concept Clinical Trial.