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Biologic and Materials Sciences and Division of Prosthodontics

Kuroda Lab Publications


Lee, S-B.; González-Cabezas, C.; Kim, K-M.; Kim, K-N. and Kuroda, K. "Catechol-functionalized synthetic polymer as a dental adhesive to contaminated dentin surface for a composite restoration." Biomacromolecules, 2015, 16(8), 2265. DOI: 10.1021/acs.biomac.5b00451.

Takahashi, H.; Akiyoshi, K. and Kuroda, K. "Affinity-mediated capture and release of amphiphilic copolymers for controlling antimicrobial activity." Chem. Comm., 2015, 51, 12597. DOI:10.1039/C5CC02012C.

Yasuhara, K. and Kuroda, K. "Kinetic study of all-or-none hemolysis induced by cationic amphiphilic polymethacrylates with antimicrobial activity." Chinese. Chem. Lett., 2015, 26, 479. [U-M Chemistry Dept. special issue] DOI:10.1016/j.cclet.2015.01.029.


Baul, U.; Kuroda, K. and Vemparala, S. "Interaction of multiple biomimetic antimicrobial polymers with model bacterial membranes." J. Chem. Phys.2014141(8), 84902. DOI:10.1063/1.4893440.

Thoma, L. M.; Boles, B. R. and Kuroda, K. "Cationic Methacrylate Polymers as Topical Antimicrobial Agents against Staphylococcus aureus Nasal Colonization." Biomacromolecules, 201415(8), 2933. DOI:10.1021/bm500557d.

Totani, M.; Ando, T.; Terada, K.; Terashima, T.; Kim, I. Y.; Ohtsuki, C.; Xi, C.; Kuroda, K. and Tanihara, M. "Utilization of star-shaped polymer architecture in the creation of high-density polymer brush coatings for the prevention of platelet and bacteria adhesion." Biomater. Sci., 20142, 1172. DOI:10.1039/C4BM00034J.

Tsukamoto, M.; Kuroda, K.; Ramamoorthy, A. and Yasuhara, K. "Modulation of raft domains in a lipid bilayer by boundary-active cur cumin." Chem. Comm., 201450(26), 3427. DOI:10.1039/c3cc47738j.


Takahashi, H.; Palermo, E. F.; Yasuhara, K.; Caputo, G. A. and Kuroda, K. "Molecular Design, Structures, and Activity of Antimicrobial Peptide-Mimetic Polymers." Macromol. Biosci., 201313(10), 1285. DOI:10.1002/mabi.201300126

Palermo, E. F.; Vemparala, S. and Kuroda, K. "Chapter 19. Antimicrobial Polymers: Molecular Design as Synthetic Mimics of Host-Defense Peptides." Tailored Polymer Architectures for Pharmaceutical and Biomedical Applications. ACS Symposium Series, 2013, Vol. 1135, 319. Chapter DOI:10.1021/bk-2013-1135.ch019

Hu, K.; Schmidt, N. W.; Zhu, R.; Jiang, Y. J.; Lai, G. H.; Wei, G.; Palermo, E. F.; Kuroda, K.; Wong, G. C. L. and Yang, L. H. "A Critical Evaluation of Random Copolymer Mimesis of Homogeneous Antimicrobial Peptides." Macromol., 201346(5), 1908-1915. DOI:10.1021/ma302577e.

Kuroda, K. and Caputo, G. A. "Antimicrobial polymers as synthetic mimics of host-defense peptides." WIREs Nanomed. Nanobiotechnol. 20135(1), 49-66. DOI: 10.1002/wnan.1199


Mizutani, M.; Palermo, E. F.; Thoma, L. M.; Satoh, K.; Kamigaito, M. and Kuroda, K. "Design and Synthesis of Self-Degradable Antibacterial Polymers by Simultaneous Chain- and Step-Growth Radical Copolymerization." Biomacromolecules, 201213(5), 1554. DOI:10.1021/bm300254s.

Palermo, E. F.; Vemparala, S. and Kuroda, K. "Cationic Spacer Arm Design Strategy for Control of Antimicrobial Activity and Conformation of Amphiphilic Methacrylate Random Copolymers." Biomacromolecules, 201213(5), 1632. DOI:10.1021/bm300342u.

Gibney, K. A.; Sovadinova, I. Lopez, A. I.; Urban, M.; Ridgway, Z.; Caputo, G. A. and Kuroda, K. "Poly(ethylene imine)s as Antimicrobial Agents with Selective Activity." Macromol. Biosci., 201212(9), 1279. DOI:10.1002/mabi.201200052


Sovadinova, I.; Palermo, E. F.; Urban, M.; Mpiga, P.; Caputo, G. A. and Kuroda, K. "Activity and Mechanism of Antimicrobial Peptide-Mimetic Amphiphilic Polymethacrylate Derivatives." Polymers, 20113, 1512. DOI:10.3390/polym3031512.

Oda, Y.; Kanaoka, S.; Sato, T.; Aoshima, S. and Kuroda, K. "Block versus Random Amphiphilic Copolymers as Antibacterial Agents." Biomacromolecules, 201112(10), 3581. DOI:10.1021/bm200780.

Han, H.; Wu, J.; Avery, C. W.; Mizutani, M.; Jiang, X.; Kamigaito, M.; Chen, Z.; Xi, C. and Kuroda, K. "Immobilization of Amphiphilic Polycations by Catechol Functionality for Antimicrobial Coatings." Langmuir, 201127(7), 4010. DOI:10.1021/la1046904.

Zimmerman, L. B.; Worley, B. V.; Palermo, E. F.; Brender, J. R.; Lee, K.; Kuroda, K.; Ramamoorthy, A. and Meyerhoff, M. E. "Absorbance-Based Assay for Membrane Disruption by Antimicrobial Peptides and Synthetic Copolymers Using Pyrroloquinoline Quinone-Loaded Liposomes." Anal. Biochem., 2011411, 194. DOI:10.1016/j.ab.2011.01.009.

Avery, C. W.; Palermo, E. F.; McLaughlin, A.; Kuroda, K. and Chen, Z. "Investigations of the Interactions between Synthetic Antimicrobial Polymers and Substrate-Supported Lipid Bilayers Using Sum Frequency Generation Vibrational Spectroscopy." Anal. Chem., 201183(4), 1342. DOI: 10.1021/ac1025804.

Palermo, E. F.; Lee, D. K.; Ramamoorthy, A. and Kuroda, K. "Role of Cationic Group Structure in Membrane Binding and Disruption by Amphiphilic Copolymers." J. Phys. Chem. B., 2011115(2), 366. DOI: 10.1021/jp1083357.

Sovadinova, I.;Palermo, E. F.; Huang, R.; Thoma, L. M.; Kuroda, K. "Mechanism of Polymer-Induced Hemolysis: Nanosized Pore Formation and Osmotic Lysis." Biomacromolecules, 201112 (1), 260. DOI: 10.1021/bm1011739.


Palermo, E. F. and Kuroda, K. "Structural determinants of antimicrobial activity in polymers which mimic host defense peptides." Appl. Microbiol. Biotechnol., 2010, 87 (5), 1605. DOI: 10.1007/s00253-010-2687-z.


Lamboy, J. A.; Arter, J. A.; Knopp, K. A.; Der, D.; Overstreet, C. M.; Palermo, E. F.; Urakami, H.; Yu, T.; Tezgel, O.; Tew, G. N.; Guan, Z.; Kuroda, K. and Weiss, G. A. "Phage Wrapping with Cationic Polymers Eliminates Nonspecific Binding between M13 Phage and High pI Target Proteins." J. Amer. Chem. Soc., 2009131(45), 16454. DOI: 10.1021/ja9050873.

Palermo, E. F.; Sovadinova, I. and Kuroda, K. "Structural Determinants of Antimicrobial Activity and Biocompatibility in Membrane-Disrupting Methacrylamide Random Copolymers." Biomacro., 200910, 3098. DOI: 10.1021/bm900784x.

Palermo, E. F. and Kuroda, K. "Chemical Structure of Cationic Groups in Amphiphilic Polymethacrylates Modulates the Antimicrobial and Hemolytic Activities." Biomacromolecules, 200910, 1416. DOI: 10.1021/bm900044x.

Kuroda, K.; Caputo, G. A. and DeGrado, W. F. "The Role of Hydrophobicity in the Antimicrobial and Hemolytic Activities of Polymethacrylate Derivatives." Chem. Eur. J., 200915, 1123-1133. DOI:10.1002/chem.200801523.